Document Details

Document Type : Thesis 
Document Title :
EFFECT OF VITAMIN D3 SUPPLEMENTATIONS ON 25-HYDROXYVITAMIN D STATUS IN HEALTHY WOMEN IN JEDDAH: IMPLICATION TO HEALTH MARKERS
تأثير مكملات فيتامين د3 على حالة 25-هيدروكسي فيتامين د لدى النساء الأصحاء في جدة: تضمين المؤشرات الصحية
 
Subject : Faculty of Science 
Document Language : Arabic 
Abstract : Effect of Vitamin D3 Supplementation on 25-hydroxyvitamin D Status in Saudi Women: Health markers may be affected by a deficiency of vitamin D and can lead to many diseases if this deficiency continues for long period of time without any treatment. Vitamin D receptors exist in many tissues. More than 200 genes constitute the target for VDR activation which shows how important vitamin D is for health. Aims were to find out the percentage of vitamin D deficiency in these women, to compare the effect of using different supplementation doses (25000 IU/week and 50000 IU/week) on raising serum vitamin D to its optimum level in three months. Moreover, to measure the effect of these doses on improving health markers. All ninety eight females aged 18-54 years were given supplements of vitamin D3 for 3 months. Vitamin D was deficient in all participants (mean=12.51±SD=6.74) ng/ml. The study was performed on two groups: group (49 subjects) which supplemented with 25000 IU/week (G25) and other (49 subjects) with 50000 IU/week (G50). The results of the analysis showed that there were significant effect of vitamin D supplementation on 25 (OH) D, PTH. Serum 25 (OH) D increased from (15.95±7.53) to (21.529.03) ng/ml in (G25), and from (8.58±3.60) to (39.4618.25) ng/ml in (G50). Supplementation with vitamin D3 showed an enhancement in some biochemical parameters that led to the improvement of important health markers. High dose vitamin D3 50000 IU/week was more effective in achieving sufficient serum 25 (OH) D compared to 25000 IU/week dose and it kept the subjects healthy. 
Supervisor : Dr. Sawsan Omar Khojah 
Thesis Type : Master Thesis 
Publishing Year : 1442 AH
2020 AD 
Added Date : Saturday, February 6, 2021 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
حنان عبدالرحمن الحارثيAlharthi, Hanan AbdurahmanResearcherMaster 

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