Document Details
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Document Type |
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Thesis |
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Document Title |
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FACTORS AFFECTING HEALTH RELATED QUALITY OF LIFE AMONG WOMEN WITH BREAST CANCER RECEIVING CHEMOTHERAPY . العوامل المؤثرة على جودة الحياة الصحية المرضات بسرطان الثدي اللاتي يخضعن للعلاج الكيميائي |
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Subject |
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Faculty of Nursing |
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Document Language |
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Arabic |
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Abstract |
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Breast cancer is the most common cancer in women worldwide. Chemotherapy is the most common therapeutic modality used in the treatment of breast cancer. It has different side effects, with associated degrees of disruption in quality of life. Health-related quality of life (HRQOL) is a multidimensional concept, considered as a subjective assessment of physical, social, psychological, and spiritual factors.
The aim of the study
To assess factors affecting HRQOL among women with breast cancer receiving chemotherapy.
Materials and methods:-
• Materials
• Study Design
Quantitative, descriptive correlational design was used in carrying out this study.
• Setting
The study was conducted at chemotherapy department, King Abdullah Medical City in Makkah.
• Sampling
A convenience sample was selected it consisted of 122 adult women diagnosed with breast cancer who receiving chemotherapy.
• Tool of the study
Three tools were used for data collection. First, was demographic and Clinical data. Second, was SF- 36 version 1, and third, was factors affecting HRQOL among women with breast cancer receiving chemotherapy questionnaire.
• Ethical approval
Written permission to conduct this study was obtained from the faculty of nursing, King Abdulaziz University. Written approval also obtained from King Abdullah Medical City in the Holy capital, Institutional Review Board.
• Validity
The content of the tools were revised by 7 experts in the field of Medical Surgical Department Faculty of Nursing at King Abdul Aziz University to test content validity, completeness, and clarity of items, comments and suggestion of experts was considered and the tool was modified accordingly
• Reliability
• The reliability of tool II: 36-Item Short form survey, version 1 has good reliability, Cronbach's alpha ranged from 0.68 to 0.94 (Frempong-Ainguah & Hill, 2014; Davies et al., 2009). In the current study, Cronbach's alpha reliability ranged from 0.71 to 0.85. The reliability of tool III has good reliability, Cronbach's alpha ranged from 0.77 to 0.82.
• A pilot was conducted on 10% of women and necessary modifications were done accordingly.
• Data collection process
After ethical approval was obtained, the data collection was started and continued for a period from March to November 2016. The researcher explained the aim of the study to participant and obtained their written consent form to participate in the study. Every woman was interviewed at her room individually for a period of 30 to 40 minutes.
• Statistical Analysis
Data ware coded, organized, fed to the computer and analysed using IBM Statistical Package for Social Sciences analysis (SPSS) software version 24.0. Quantitative data were described using frequency and percentages, means and standard deviations. Comparison between different groups regarding categorical variables was tested using T-test or ANOVA. Pearson correlation coefficient was used for the p-value in each of the comparisons less than 0.01 and 0.05.
The main results of the study were:
• Nearly half the sample (45.0%) of studied women were in the age group of (40 < 50) years.
• More than half (58.2%) of the studied women were married.
• More than two third (79%) of studied women had no family history with breast cancer.
• More than half (59.8%) of the studied women had no chronic diseases and only nearly quarter (8.2%), (18%) had diabetes mellitus and hypertension.
• The majority (80.3%) of the studied women had amenorrhea.
• (41.8%) of studied women with breast cancer receiving chemotherapy were overweight.
• About nearly quarter of studied women had neutropenia.
• More than half (51.6%) of studied women with breast cancer receiving chemotherapy had moderately affected by overall physical factors.
• The majority (84.4%) of studied women with breast cancer receiving chemotherapy had moderately affected by overall social factors.
• Nearly two third (72.1%) of studied women with breast cancer receiving chemotherapy had moderately affected by overall psychological factors.
• More than half (56.0%) of studied women with breast cancer receiving chemotherapy were moderately affected by overall spiritual factors.
• Women with breast cancer receiving chemotherapy had moderate level regarding overall QOL.
• There was a statistically significant negative relationship between overall factors affecting health and overall QOL (r= -.465**, P-value < 0.000) of women with breast cancer receiving chemotherapy.
• There was statistically significant negative relationship between psychological factors and overall QOL level (r= -.289-**, P- value < 0.001) of women with breast cancer.
• There was statistically significance difference between age group and physical factors P < 0.05.
• There was statistically significance difference between stages of breast cancer and psychological factors P < 0.05.
Conclusion:
In conclusion, more than half of the studied women with breast cancer receiving chemotherapy had moderate level regarding overall factors affecting health related quality of life. The majority of studied women with breast cancer receiving chemotherapy had moderately affected by overall social factors and nearly two third had moderately affected by overall psychological factors. While more than half were moderately affected by overall physical and spiritual factors. Moreover, women with breast cancer receiving chemotherapy had moderate level of overall QOL. There was a statistically significant negative relationship between overall factors affecting health and overall women’ QOL. There was statistically significance difference between age group and physical factors.
6.2 Recommendations:
• Quality of life assessments should be done by nurses regarding women with breast cancer in treatment protocols to improve their quality of life.
• Developed assessment guidelines and management booklet about the side effects of chemotherapy.
• Establishing self-care practices educational program about the side effects of chemotherapy and how to manage it.
• Further researches are needed to get a better understanding of women perception, attitude and practice regarding chemotherapy side effects. |
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Supervisor |
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Dr. Gihan Mohamad Ali |
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Thesis Type |
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Master Thesis |
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Publishing Year |
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1439 AH
2018 AD |
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Co-Supervisor |
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Dr. Samah Mahmod Sofar |
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Added Date |
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Tuesday, June 5, 2018 |
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Researchers
| صالحة حامد الشيخ | Al Shaikh, Salehah Hamid | Researcher | Master | |
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