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Document Type |
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Article In Journal |
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Document Title |
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Glutamine-synthesizing activity in lungs of fed, starved, acidotic, diabetic, injured and septic rats Glutamine-synthesizing activity in lungs of fed, starved, acidotic, diabetic, injured and septic rats |
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Subject |
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Biochemistry |
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Document Language |
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English |
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Abstract |
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The maximal catalytic activity of glutamine synthetase was measured in lung homogenates of the rat (being 5.46 +/- 0.29 mumol/min per g wet wt. or 31.70 +/- 2.62 nmol/min per mg of protein at 37 degrees C, in fed animals). The activity is similar to that of liver, but 16-fold higher than that in quadriceps muscles. Chronic (NH4Cl-induced) or acute (HCl-induced) metabolic acidosis had no effects on enzyme activity, but there was a marked increase in the activity of glutamine synthetase in starved (30-40%), streptozotocin-diabetic (17%), dexamethasone-treated (18-22%), laparotomized (25-27%) and septic rats (24-45%) |
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ISSN |
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0264-6021 |
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Journal Name |
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The Biochemical Journal |
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Volume |
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570 |
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Issue Number |
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3 |
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Publishing Year |
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1411 AH
1990 AD |
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Article Type |
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Article |
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Added Date |
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Monday, December 5, 2011 |
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Researchers
| محمد العرضاوي | Ardawi, Mohammed | Researcher | Doctorate | |
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