Document Details

Document Type : Article In Journal 
Document Title :
Lack of detection of human papillomavirus infection by hybridization test in prostatic biopsies
Lack of detection of human papillomavirus infection by hybridization test in prostatic biopsies
 
Subject : Virology 
Document Language : English 
Abstract : OBJECTIVE: To explore the possibility of finding human papillomavirus (HPV) infection in the prostate tissue of a cohort of Saudi men presenting with benign prostatic hyperplasia (BPH) or prostate cancer. METHODS: A cohort study on prospectively collected tissue samples was conducted at King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia from March 2007 to December 2008 on a total of 56 male patients, age range 50-93 years (average 68), diagnosed as having BPH or prostate cancer. The HPV DNA hybridization by hybrid capture 2 technology was performed on prostate biopsies of these patients to detect 18 types of HPV infection, and differentiate between 2 HPV DNA groups, the low-risk types, and the high/intermediate risk types. RESULTS: The tissues of all the prostatic biopsies were negative for HPV DNA. CONCLUSION: Our results, using the hybridization test, indicate that it is unlikely that HPV-16 or HPV-18, or the other tested subtypes, enhance the risk of prostate cancer 
ISSN : 0379-5284 
Journal Name : The Saudi Medical Journal 
Volume : 30 
Issue Number : 5 
Publishing Year : 1430 AH
2009 AD 
Article Type : Article 
Added Date : Sunday, July 10, 2011 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
فاتن قزازGazzaz, Faten InvestigatorDoctoratefatengazzaz@hotmail.com
هشام موصليMosli, Hisham ResearcherDoctorate 

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