Document Details Document Type : Article In Journal  Document Title : Parental Factors in Childhood Malignancies Parental Factors in Childhood Malignancies   Document Language : English  Abstract : current study included 125 children with can¬cer attending the paediatric Oncology Clinic at KAAII & OC during the years 1999 & 2000. One hundred and twenty-five, age and sex matched healthy children were also included as a control group. Forty eight per¬cent of the cancer group were coming from rural plac¬es versus 3 5.2% of the controls. This difference was statistically significant. As regards the degree of con¬sanguinity, there was statistically significant high prevalence of first degree of consanguinity among children of cancer group than the controls. This was true for children with solid tumors but not for children with lymphoma and leukemia. In 14 cases of the can¬cer group there was family history of cancer (11.2%) versus 5 cases of the control group (4%). This differ¬ence was statistically significant (p=0.02). Among the cancer group 57 children (45.6%) were breast-fed for more than 6 months versus 76 children'(60.8%) of the control group. This difference was statistically sig-nificant (p=0.0l). There was no significant difference regarding the parental educational status between the cancer and control groups. However, parental smoking was more prevalent among children with cancer than among the other group. This difference was statistical¬ly significant for paternal smoking (p=0.0l). Studying the maternal infection and drug intake three months before and during pregnancy in the cancer and control groups, there was no difference between the two groups. There was more maternal exposures to paints and dyes as well as radiation 3 months before and during pregnancy in the cancer group than in the control group, 9.6% versus 5.6% and 1.6% versus 0.8%, respectively. However, these differences were not statistically significant. As regards paternal expo¬sures, there was statistically significant more expo¬sures to motor exhaust products in the cancer group than in the control group (p=0.04), In order to identify the possible factors playing roles in the etiology of childhood cancer in K.S.A. we are in need of detailed investigations and further studies including larger groups of patients. These studies should be multicen¬tric and nation wide. As it is better to prevent rather than to treat, there is a potential to prevent at least some of childhood cancer by reducing or eliminating exposure to risk factors. Key words: Childhood cancer-Malignancy  ISSN : 7897775  Journal Name : Med. J. Cairo Univ  Volume : 71  Issue Number : 2  Publishing Year : 1424 AH 2003 AD  Article Type : Article  Added Date : Saturday, January 15, 2011  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email محمود الاحول AI-Ahwal, Mahmoud Researcher Doctorate   Files File Name Type Description  28623.doc doc   Back To Researches Page