Document Details

Document Type : Article In Journal 
Document Title :
Non-neoplastic changes in gastric antrum: Are they different in distally located intestinal and diffuse type gastric adenocarcinoma?
Non-neoplastic changes in gastric antrum: Are they different in distally located intestinal and diffuse type gastric adenocarcinoma?
 
Document Language : English 
Abstract : A total of 126 cases of primary adenocarcinoma of distal (antrum and/or adjacent body) stomach were reviewed. These cases were collected from the histopathology laboratory of Asir Central Hospital, Southwestern Saudi Arabia over an 8 year period (1987-94). Only gastrectomy specimens with non-neoplastic antral mucosa available for histological examination were included. Of 126 cases, 85 (67.5%) were of the intestinal type and 41 (32.5%) were of the diffuse type. Histological examination of the non-neoplastic antral mucosa showed: gastritis in 100% of these cases; Helicobacter pylori in 103/126 cases (81.8%); multifocal atrophic gastritis (MAG) in 53/126 cases (42.1%); intestinal metaplasia (IM) in 62/126 (49.2%); and type III intestinal metaplasia in 30/62 cases (47.7%). None of these non-neoplastic changes of antral mucosa was significantly different when the prevalence of these changes in intestinal and diffuse type gastric adenocarcinoma were compared using the chi 2 test. The prevalence of these non-neoplastic lesions were calculated in a 126 dyspeptic age- and sex-matched control patients and were as follows: H. pylori 91%; gastritis 78%; MAG 7.4%; IM 19% and type III IM 1.6%. The prevalence of H. pylori bacilli and gastritis was not significantly different between the cancer patients and the controls. The prevalence of MAG, IM and type III IM was significantly higher among cancer patients compared with the control group. 
ISSN : 9237067 
Journal Name : Europ J Cancer Prevention 
Volume : 6 
Issue Number : 2 
Publishing Year : 1417 AH
1997 AD 
Article Type : Article 
Added Date : Monday, May 17, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
عواطف جمالJamal, Awatif ResearcherDoctorateAwatjamal@yahoo.com

Files

File NameTypeDescription
 26729.doc doc 

Back To Researches Page