Document Details Document Type : Article In Journal  Document Title : NEUTROPENIA IN SYSTEMIC LUPUS ERYTHEMATOSUS NEUTROPENIA IN SYSTEMIC LUPUS ERYTHEMATOSUS   Document Language : English  Abstract : Background: systemic lupus erythematosus (SLE) is a multisystem disease of unclear eitiology .Neutropenia occurs in approximately half of SLE patients .Infection is a major cause of morbidity and mortality in those SLE patients . Multiple causes have been involved in the increased susceptibility to infection in such patients. Objectives : This study was conducted to document the frequency of neutropenia and its implication on infection risk among our SLE patients. Methodology: Retrospectively, we studied 61 SLE patients from January 2000 to December 2005. Information collected included age, sex, nationality, absolute neutrophil count and history of infection before treatment. Results: Sixty one patients were found to have SLE, 91.8% were females, while males were 8.2% with a female to male ratio of 11.2:1. The mean age of SLE patients was 26.27 years with a SD + 10.06.Neutropenia was found in 47.4% of patients, 69% of them had moderate to severe type.Infections were documented in 31.1% of SLE patients, 63.1% of them were neutropenic. Urinary tracts followed by chest were the two main sites for infection. Conclusion: In the current study, neutropia is common among our SLE patients. Infection was demonstrated in about one third of the cases, the majority of them were neutropenic. However, neutropenia is one among multiple causes for decreases resistance to infection in untreated active SLE patients.  ISSN : 1319-1004  Journal Name : Egypt Rheumatol Rehabilitation  Volume : 33  Issue Number : 1  Publishing Year : 1426 AH 2006 AD  Article Type : Article  Added Date : Sunday, April 18, 2010  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email العنود الجفري AL-JIFRI, AL-ANOUD Researcher Doctorate anoud_jif@hotmail.com فاتن السايس AL-SAYES, FATIN Researcher Doctorate fatinsayes@yahoo.com Files File Name Type Description  26544.doc doc   Back To Researches Page