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Document Type |
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Article In Journal |
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Document Title |
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Beneficial effects of chromium supplementation in Saudi subjects with type I, and type II diabetes Beneficial effects of chromium supplementation in Saudi subjects with type I, and type II diabetes |
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Document Language |
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English |
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Abstract |
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Background of Study: The role of chromium (Cr) in improving glucose tolerance has been reported since the sixties . Supplementation studies confirmed this in different
countries .Since Chromium is a nutrient , only deficient subjects will benefit . Diabetes is a serious problem is Saudi Arabia , and the extent of chromium deficiency is
not known.
Objectives: To investigate chromium status in Saudi subjects with type I and type II diabetes and assess the effect of chromium supplementation.
Methods: Seventy eight NIDDM and 30 IDDM patients were divided randomly into two groups each , and given Cr supplement as brewer's yeast and Crl3 sequentially
with placebo in between, in a double-blind , cross over design of four stages, each lasting 8 weeks. At the beginning and end of each stage , subjects were weighed, their
dietary data and drug dosage recorded, and blood samples collected for analysis of glucose (fasting and 2L post 75g glucose load) fructosamine and lipid profile.
Results: Both supplements caused a significant decrease in the means of glucose (fasting and post glucose load) fructosamine and triglycerides, and increased the
mean HDL-cholesterol in type II diabetic subjects. The mean drug dosage decreased slightly and significantly in the case of glibenclamide. However, in type I diabetic
subjects, this was only noted when brewer's yeast was given.
Conclusions: Chromium deficiency exists in Saudi subjects since chromium supplementation helped in the control of glucose and improved lipid variables. Chromium
supplements are cheap and could help to cut cost of this chronic disorder. A larger scale study is needed to help decide on the appropriate chemical form and dosage
required to achieve optimal response. |
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ISSN |
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11575393 |
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Journal Name |
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Proceedings of the 12th international congress of endocrinology |
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Volume |
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1 |
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Issue Number |
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1 |
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Publishing Year |
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2004 AH
2004 AD |
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Article Type |
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Article |
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Added Date |
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Wednesday, March 24, 2010 |
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Researchers
| سهاد باحجري | BAHIJRI, SUHAD | Researcher | Doctorate | |
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