Document Details

Document Type : Article In Journal 
Document Title :
Adrenal Insufficiency Secondary to Exogenous Use of Dermatological Steroid
Adrenal Insufficiency Secondary to Exogenous Use of Dermatological Steroid
 
Subject : Endocrinology 
Document Language : English 
Abstract : During years 2000 and 2003, a total of 146 patients were diagnosed to have adrenal insufficiency due to exogenous use of steroid. 20 (13.69%) of these patients were diagnosed to have pituitary-adrenal suppression secondary to exogenous use of dermatological steroid. The objective of the study is to identify the duration of steroid use, clinical presentation and the results of the assessment of pituitary-adrenal axis. Fatigability, body pain, and abdominal pain were the main symptoms at presentation. All of these patients showed signs of Cushing's syndrome (chronic high steroid exposure). Low urinary and serum cortisone levels, low adrenocorticotropic hormone levels and blunt response to adrenocorticotropic hormone injection were found in all patients. Symptoms of patients improved with replacement therapy with oral steroids. We concluded that local dermatological steroid preparations has similar complication on the pituitary-adrenal axis as the other routes of systemic steroid administration but with prolonged period of exposure for a year or more 
ISSN : 1319-1004 
Journal Name : Medical Science Journal 
Volume : 12 
Issue Number : 1 
Publishing Year : 1425 AH
2005 AD 
Article Type : Article 
Added Date : Thursday, October 15, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
عبدالرحمن الشيخAl-Shaikh, AbdulRahman ResearcherDoctorate 

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