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Document Type |
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Thesis |
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Document Title |
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Effect of Barley, Cinnamon and Their Combination on Type 2 Diabetic Rats تأثير الشعير و القرفة و خليطهما على الفئران المصابة بداء السكري من النوع الثاني |
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Document Language |
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English |
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Abstract |
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Objective: The aim of the present study was to investigate the effect of supplementation with cinnamon, barley and their combination on glycemia, dyslipidemia and adipose tissue hormones in type 2 diabetes. Methods: Thirty five male Wistar rats were divided into six groups as follows: negative (non-diabetic) and positive (diabetic) control groups, a diabetic group fed 5% cinnamon, a diabetic group fed 30% barley, and a diabetic group fed 5% cinnamon and 30% barley. Biochemical analysis of fasting blood glucose, serum insulin, lipid profile in addition to adiponectin and leptin were done at baseline and at the end of the experimental period (8weeks). Results: Blood glucose concentration significantly decreased in all treated diabetic rats compared with diabetic untreated group. Also, serum insulin and high density lipoprotein cholesterol levels were significantly increased while total cholesterol, triglycerides and low-density lipoprotein cholesterol were significantly decreased after eight weeks of supplementation. Regarding adipocytes hormones, adiponectin showed significant increment while leptin showed significant reduction after treating diabetic rats with cinnamon, barley and their combination. No significant differences were observed between the effects of the three treatments on all studied parameters. Histopathological studies of rats pancreas showed that combination of cinnamon and barley caused obvious improvement in insulin positive cells followed by cinnamon alone. Conclusion: Supplementation with cinnamon, barley and their combination have a regulatory role in blood glucose level, lipid profile and adipocytes hormones in type 2 diabetic rats and the most effective material used was the combination of cinnamon and barley. |
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Supervisor |
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Dr. Lamiaa Ali Ahmed |
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Thesis Type |
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Master Thesis |
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Publishing Year |
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1433 AH
2012 AD |
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Number Of Pages |
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101 |
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Co-Supervisor |
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Dr. Maha Mohammed Badkook |
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Added Date |
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Thursday, September 10, 2015 |
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Researchers
| إسراء محمد شطوان | Shatwan, Israa Mohammed | Researcher | Master | Shatwan1@hotmail.com |
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