Document Details Document Type : Article In Journal  Document Title : Malignant eccrine poroma Malignant eccrine poroma   Document Language : English  Abstract : Benign eccrine poroma arises from the intraepidermal portion of the eccrine gland duct. Malignant transformation is rare and should be suspected when these lesions present with pain, bleeding or itching. We report a 44-year-old male patient who presented primarily with a lesion diagnostic of benign eccrine poroma of the right foot sole with no clear evidence of malignancy, which was incompletely excised, followed 5 months later by local recurrence, ulceration, occasional bleeding and right inguinal lymphadenopathy. Incomplete excision of the primary tumor as well as excision of a skin lesion on the right knee joint revealed malignant eccrine poroma with aggressive histology, lymphovascular and perineural invasion. Investigations revealed no evidence of distant metastasis. This tumor might be malignant at the first presentation, which was not confirmed histopathologically considering the short duration of only 5 months for malignant transformation. The patient received 3 cycles of Docetaxel Taxotere, Cisplatin combination chemotherapy with partial response. The management of metastatic malignant eccrine poroma is difficult. It has proven resistant to many chemotherapeutic agents and radiotherapy  ISSN : 0379-5284  Journal Name : The Saudi Medical Journal  Volume : 26  Issue Number : 10  Publishing Year : 1426 AH 2005 AD  Article Type : Case Report  Added Date : Monday, August 31, 2009  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email سمير زمو Zimmo, Sameer Researcher Doctorate   علي صوان Sawan, Ali Researcher Doctorate   Files File Name Type Description  28971.pdf pdf   Back To Researches Page