Document Details Document Type : Article In Journal  Document Title : Defective Collagen Metabolism in Saudi Patients with Hernia Defective Collagen Metabolism in Saudi Patients with Hernia   Subject : General Surgery  Document Language : English  Abstract : Fibroblastic cell cultures were derived from the hernial sac and some of the surrounding muscles (rectus sheath, internal oblique, and/or cremasteric muscle) of 130 Saudi patients with different types of herniation, and from 21 control subjects. The rates of cell proliferation were studied for 39 days. Results suggested decreased rates of proliferation of cells derived from patients compared to controls. In vitro studies of the rates of incorporation of 14C proline into the muscle biopsies revealed decreased rates of label incorporation in the samples derived from patients compared to controls. However, no differences were detected between rates of collagenase activities of the biopsies obtained from patients compared to those of controls. These findings suggest that collagen synthesis is probably defective in the studied group of Saudi patients with hernia  ISSN : 0004-5632  Journal Name : Annals of Clinical Biochemistry  Volume : 29  Issue Number : 4  Publishing Year : 1412 AH 1992 AD  Article Type : Article  Added Date : Saturday, August 22, 2009  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email محمد عجب نور Ajabnoor, Mohammed Investigator Doctorate   أحمد مختار Mokhtar, Ahmed Researcher Doctorate   عادل عبدالرافع AbdulRafee, Adel Researcher Doctorate   علي طه Taha, Ali Researcher Doctorate   Files File Name Type Description  29340.zip zip   Back To Researches Page