Document Details

Document Type : Article In Journal 
Document Title :
Potentiometry, Stability and Thermodynamics of Diethyltin(IV) Dichloride with Some Selected Biomolecules
Potentiometry, Stability and Thermodynamics of Diethyltin(IV) Dichloride with Some Selected Biomolecules
 
Document Language : English 
Abstract : The interaction of diethyltin(IV), DET, with selected bioligands having a variety of model functional groups was investigated at 25 A degrees C and ionic strength 0.1 mol center dot dm(-3) NaCl using the potentiometric technique. The hydrolysis constants of the DET cation and the formation constants of the complexes formed in solution were calculated using the MINIQUAD-75 program. The stoichiometry and stability constants for the complexes formed are reported. The results show the formation of 1:1 and 1:2 complexes with amino acids and DNA constituents. The dicarboxylic acids form 1:1 complexes. The peptides form both 110 complexes and the corresponding deprotonated amide species [Et2Sn(LH-1)] (11-1). The participation of different ligand functional groups in binding to organotin is discussed. The concentration distributions of the various complex species were evaluated as a function of pH. The standard thermodynamic parameters Delta HA degrees and Delta SA degrees, calculated from the temperature dependence of the equilibrium constants, were investigated for the interaction of DET with thymine as a representative example of DNA constituents. The effect of ionic strength and solvent on hydrolysis constants of DET, protonation equilibria of thymine and its complex formation with DET were investigated and discussed. 
ISSN : 0095-9782 
Journal Name : JOURNAL OF SOLUTION CHEMISTRY 
Volume : 42 
Issue Number : 11 
Publishing Year : 1434 AH
2013 AD 
Article Type : Article 
Added Date : Wednesday, July 19, 2017 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
M AljahdaliAljahdali, m Researcher  
A AbdelkarimAbdelkarim, A Researcher  
A El-SherifEl-Sherif, A Researcher  

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