تفاصيل الوثيقة نوع الوثيقة : مقال في مجلة دورية  عنوان الوثيقة : Growth hormone for children with chronic renal failure and on dialysis Growth hormone for children with chronic renal failure and on dialysis   لغة الوثيقة : الانجليزية  المستخلص : We studied all children with CRF who received recombinant human growth hormone (rhGH) for more than a year (mean+/-SD duration of therapy 3.7+/-2.5 years) over an 11-year period. There were 32 children. Twenty-one children were conservatively managed, with a mean glomerular filtration rate (GFR) of 24+/-12 mL min(-1)/1.73 m2 at the start of rhGH. Their height standard deviation score improved from -2.5+/-1.4 to -2.1+/-0.7 at 1 year (P=0.3), -2.0+/-0.7 at 2 years (P=0.01), and -1.6+/-0.6 at 3 years (P=0.001). After that there was no improvement. Eleven children were on dialysis, six on haemodialysis (HD) and five on peritoneal (PD). Ht SDS improved from -2.7+/-0.5 to -2.3+/-0.5 at 1 year (P=0.02). Thereafter there was no further improvement. RhGH was stopped because of transplantation in 29 patients at a mean+/-SD age of 12.1+/-4.0 years. Mean Ht SDS was -1.8+/-0.8 at transplant and there was no change over the following 5 years. In conclusion, treatment with rhGH resulted in improvement in Ht SDS in conservatively managed CRF for up to 3.0 years and for 1 year in children on dialysis. Discontinuation of rhGH after transplantation resulted in little change in Ht SDS  ردمد : 0931-041X  اسم الدورية : Pediatric Nephrology  المجلد : 20  العدد : 5  سنة النشر : 1426 هـ 2005 م  نوع المقالة : مقالة علمية  تاريخ الاضافة على الموقع : Sunday, March 16, 2008  الباحثون اسم الباحث (عربي) اسم الباحث (انجليزي) نوع الباحث المرتبة العلمية البريد الالكتروني جميلة قاري Kari, Jameela باحث رئيسي دكتوراه   الملفات اسم الملف النوع الوصف  X30M381404466271(growth hormone).pdf pdf مشاهدة المقالة العلمية كاملة الرجوع إلى صفحة الأبحاث