تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Distortion product otoacoustic emission for the screening of cochlear damage in children treated with cisplatin
Distortion product otoacoustic emission for the screening of cochlear damage in children treated with cisplatin
 
الموضوع : الأنف والأذن والحنجرة 
لغة الوثيقة : الانجليزية 
المستخلص : OBJECTIVES/HYPOTHESIS: To detect subtle hearing changes by measuring otoacoustic emissions in patients treated with a first dose of cisplatin. STUDY DESIGN: Prospective study. METHODS: We recruited 26 patients (mean age at treatment, 11.3 years) into this prospective study conducted at a tertiary academic referral center. Audiograms and transient-evoked otoacoustic emissions (TEOAEs) and distortion-product otoacoustic emissions (DPOAEs) were measured before and after the first dose of cisplatin. RESULTS: Baseline readings were compared with those recorded after the administration of the first dose of cisplatin. Two patients showed a loss of TEOAEs at high frequencies above 4 kHz, and this was consistent with the 25-dB hearing loss of the high frequencies detected in their audiograms; there was a significant threshold shift for DPOAEs at a frequency >3 to 4 kHz (P <.05). CONCLUSIONS: DPOAE testing appears to be a more sensitive method to detect cochlear damage than conventional pure-tone audiometry. Our results suggest that the measurement of DPOAE thresholds is a useful approach to detect the early auditory changes induced by cisplatin therapy 
ردمد : 0023-852X 
اسم الدورية : The Laryngoscope 
المجلد : 121 
العدد : 5 
سنة النشر : 1432 هـ
2011 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Wednesday, August 3, 2011 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
خالد النوريAl-Noury, Khalid باحثدكتوراه 

الملفات

اسم الملفالنوعالوصف
 30005.pdf pdf 

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