تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
“Ciliary neurotrophic factor immunoreactivity in rat intramuscular nerves and neuromuscular junctions”
“Ciliary neurotrophic factor immunoreactivity in rat intramuscular nerves and neuromuscular junctions”
 
لغة الوثيقة : الانجليزية 
المستخلص : In order to better understand the role played by the ciliary neurotrophic factor (CNTF) during nerve growth, we have investigated the localization of this factor in normal skeletal muscle and neuromuscular junctions of the rat. In addition, we have investigated the changes in CNTF immunoreactivity in botulinum-toxin-paralyzed rat muscle. This animal model was characterized by local muscle inactivity which was accompanied by profuse terminal nerve growth. The results showed that CNTF immunoreactivity in normal rat muscle was localized in Schwann cells surrounding myelinated intramuscular- and preterminal nerve fibres. No staining was seen in Schwann cells overlying the unmyelinated nerve terminals nor within axons or nerve terminals. Secondly, we have demonstrated that CNTF immunoreactivity did not show any changes in botulinum-toxin-paralyzed muscle from the control muscle (neither during terminal nerve growth nor during the formation of new neuromuscular junctions). In view of the present findings, and previous reports, it is suggested that CNTF has no role during growth of nerve fibres, but rather during the process of myelination, or perhaps, thickening and maturation of nerve fibres. 
ردمد : 3185-4152 
اسم الدورية : Al-Azhar Medical Journal 
المجلد : 4 
العدد : 32 
سنة النشر : 2003 هـ
2003 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Sunday, March 28, 2010 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
شريف حسنHassan, Sherif باحثدكتوراه 

الملفات

اسم الملفالنوعالوصف
 26223.1 1 

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